Written by: Dr. Andrew Akhaphong, DCN, MS, RD, LD, Mackenthun’s Fine Foods Registered Dietitian
Updated: February 5, 2026
When cholesterol runs high, advice like “avoid red meat,” “cut out red meat,” or “eat more plants” is often among the first recommendations from healthcare providers. Although these strategies can improve cholesterol levels in some individuals, added sugars are a common dietary factor that can contribute to elevated cholesterol. Added sugars refer to sugars that are incorporated into foods and beverages beyond what occurs naturally. Examples include honey, cane sugar, table sugar, high-fructose corn syrup, agave syrup, and similar sweeteners.
Why Are Added Sugars in Food?
How Does Added Sugar Affect Cholesterol?
After sugar is broken down into glucose, it enters the bloodstream as blood sugar. To keep levels balanced, the pancreas releases insulin and glucagon. When blood sugar rises, insulin directs glucose into the liver, muscles, and fat for energy or storage as glycogen. If there’s more glucose than the body needs, the liver can turn the excess into cholesterol. Cholesterol helps the body make hormones like testosterone and estrogen and absorb nutrients like vitamins D and A. But when LDL, or “bad” cholesterol, builds up more than the good, it can increase the risk for heart disease. Our liver can also turn excess glucose into a fatty acid called triglycerides. Oftentimes higher triglycerides lead to high LDL cholesterol levels.
Reducing Added Sugars